欧盟评估一种L-精氨酸作为所有动物饲料添加剂的安全性和有效性
By: Date: 2022-08-01 Categories: newsguide Tags: ,
   食品伙伴网讯  2022年7月29日,据欧盟食品安全局(EFSA)消息,应欧盟委员会要求,欧盟动物饲料添加剂和产品(FEEDAP)研究小组就谷氨酸棒杆菌CGMCC 20516生产的L-精氨酸(l-arginine)作为所有动物饲料添加剂的安全性和有效性发表科学意见。

 
  经过评估,专家小组认为在拟议的使用条件下,该添加剂对目标物种是安全的,但无法对使用者的安全性做出结论。评估中的添加剂被认为是非反刍动物物种必需氨基酸L-精氨酸的有效来源。为了使补充的L-精氨酸对反刍动物和非反刍动物同样有效,需要防止其在瘤胃中降解。部分原文报道如下:
 
  Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of the feed additive consisting of l-arginine produced by fermentation using a non-genetically modified strain of Corynebacterium glutamicum (CGMCC 20516). The additive is intended to be used in feed and water for drinking for all animal species and categories. The production strain was considered suitable for the qualified presumption of safety (QPS) approach to safety assessment. No viable cells of C. glutamicum CGMCC 20516 were detected in the final product. l-Arginine produced using C. glutamicum CGMCC 20516 is safe for the target species when supplemented in appropriate amounts to the diet according to the nutritional needs of the target species, for the consumer and for the environment. In the absence of data, the FEEDAP Panel could not conclude on the safety of l-arginine produced by C. glutamicum CGMCC 20516 for the users. The additive l-arginine produced by fermentation using C. glutamicum CGMCC 20516 is regarded as an efficacious source of the essential amino acid l-arginine for non-ruminant species. For the supplemental l-arginine to be as efficacious in ruminants as in non-ruminant species, it requires protection against degradation in the rumen.
 
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