Soil nitrogen shortage is the main factor limiting crop production. Analyzing the genetic and molecular mechanism of crop nitrogen efficiency from the whole genome level, cultivating new varieties of nitrogen efficient crops, and improving the nitrogen use efficiency of crops are the key to solve the non-point source pollution of agriculture in China and the world, realize the sustainable development of agriculture, and protect the environment. Recently, the high performance computing Department of the computer network information center of the Chinese Academy of Sciences, the State Key Laboratory of plant cell and chromosome engineering of the Institute of genetic development of the Chinese Academy of Sciences, and Ludong University have made important progress in the study of molecular mechanisms for the efficient use of nitrogen in Wheat by using genome sequencing and bioinformatics. On July 22, the relevant research results were published in comparative genomic and transScriptomic analyses uncovered the molecular basis of high nitrogen use efficiency in the what cultural Kenong 9204, published online on molecular plant.
This research focuses on the large-scale genome, transcriptome, epigenome and important gene functions of the nitrogen efficient wheat variety”konong 9204″. Based on bioinformatics and high-performance computing technology, the research team of the high-performance computing Department has developed algorithms and software for large-scale genome parallel assembly and annotation, and assembled the high-quality genome sequence of”konong 9204″, And systematically annotated and analyzed the genes related to nitrogen absorption and metabolism of”konong 9204″. Compared with the nitrogen inefficient variety”Jing 411″, the study identified the key developmental stages and related major metabolic pathways of wheat in response to nitrogen deficiency (Fig. 1 and 2), which provided a new perspective on the molecular mechanism of nitrogen efficiency in wheat, and provided valuable genetic resources for the cultivation of new nitrogen efficient wheat varieties.
The research work is supported by the innovative research group project/major research plan project of the National Natural Science Foundation of China, the strategic leading science and technology project of the Chinese Academy of Sciences, and the informatization project of the Chinese Academy of Sciences during the 13th five year plan.