The Food Safety Testing Group of Guizhou University published a paper in the Journal of Agricultural and Food Chemistry
By: Date: 2021-03-25 Categories: foodtechnology Tags: ,
  Guizhou University The Food Safety Testing Research Group led by Professor Wu Yuangen from the School of Wine and Food Engineering has recently used nucleic acid aptamers to regulate the production of tungsten disulfide nanosheets. Peroxidase mimics enzyme activity, and a new method for sensitive and colorimetric detection of kanamycin residues in food has been constructed. The relevant results were published in the Journal of Agricultural and Food Chemistry (JAFC) on March 1, 2021. on. JAFC is published by the American Chemical Society (ACS). It is an international authoritative journal in the field of food science and agriculture and forestry sciences. The latest impact factor is 4.192 (2019). It is listed as zone 1 in the basic and upgraded versions of the Chinese Academy of Sciences.
The Food Safety Testing Group of Guizhou University published a paper in the Journal of Agricultural and Food Chemistryimage
  Article online publication link URL:https://pubs .acs.org/doi/10.1021/acs.jafc.1c00925
The Food Safety Testing Group of Guizhou University published a paper in the Journal of Agricultural and Food Chemistryimage(1)

  Kanamycin aptamer colorimetric sensor Schematic diagram of detection principle

   This research group has thoroughly studied the interaction mechanism between two-dimensional nanosheets, aptamers and kanamycin, and found that the Guanine bases have a significant enhancement effect on the activity of tungsten disulfide peroxidase mimics. This research effectively combines the specific recognition ability of nucleic acid aptamers and the catalytic regulation of nanozymes, constructing a general platform suitable for food hazard detection, and provides new ideas for the design of other nanozyme biosensors.
The Food Safety Testing Group of Guizhou University published a paper in the Journal of Agricultural and Food Chemistryimage(2)< br/>
  WS2Nano sheet TEM image (a) and AFM image (b); (c) Agarose gel electrophoresis study of the interaction between Ky2 aptamer and WS2 nanosheets; (d) WS22 before and after the addition of Ky2 aptamer sub>Change of average particle size of nanosheets; (e) Change of Zeta potential before and after adding Ky2 aptamer; (f) Effect of nucleic acid base composition on peroxidase activity of WS2 nanosheets .

  Introduction to the first author:

   Tangyue, female, graduated from Guizhou University with a bachelor’s degree in bioengineering in June 2014, and is currently a 2018 graduate student majoring in applied biotechnology at the College of Wine and Food Engineering. The student used the simulated enzyme activity of layered WS2 nanosheets to establish a new method for colorimetric detection of heavy metal lead ions. As the first author, the relevant results were published in the international analytical journal Analytica Chimica Acta (Class 2 of the Chinese Academy of Sciences, IF =5.997). This student has successively won awards and honorary titles such as the National Postgraduate Scholarship, the Postgraduate Excellence Scholarship of Guizhou University, the Three Good Postgraduates of Guizhou University, the second-class academic scholarship of Guizhou University, and the outstanding party worker of the School of Brewing and Food Engineering.

  Introduction to the corresponding author:

  Wu Yuangen, male, Ph.D., professor, received his Ph.D. from Shanghai Jiaotong University in 2014, and was selected as a high-level innovative talent program in Guizhou Province, Guizhou University”Young Talents” In the past five years, he has won the first “Guohua Award” of Guizhou University, the first prize of “Excellence Award” of Guizhou University, and the third prize of Guizhou University’s first young teacher teaching competition. He presided over the completion of 3 National Natural Science Foundations. , Guizhou Science and Technology Fund key projects and Guizhou Science and Technology Support Program, etc., in well-known journals such as Journal of Agricultural and Food Chemistry, Chemical Communications, Journal of Colloid and Interface Science, Nanoscale, Sensors and Actuators B:Chemical, Analytica Chimica Acta, etc. He has published more than 30 SCI papers, and his signed papers have been cited by SCI more than 1,000 times. The current research interest of the subject is to use Capture-SELEX technology to screen the nucleic acid recognition ligands of food small molecule hazards, and use precious metals, inorganic nanomaterials, organic small molecules as signal carriers to establish nucleic acid aptamer recognition and nanoenzyme catalysis. New methods of food safety inspection and quick inspection of products.