In the past few decades, obesity has become an international public problem, increasing the risk of diseases in most countries and regions. Obesity is closely related to many chronic metabolic diseases, such as hypertension, cardiovascular disease, inflammation, type 2 diabetes and cancer. Therefore, the prevention and treatment of obesity is receiving more and more attention from researchers. In recent years, more and more natural foods or their functional components have been proven to have biologically active functions such as reducing dyslipidemia, reducing inflammation and treating obesity.
As an important by-product of rice processing, rice bran has the function of preventing or improving many diseases. However, the internal correlation between rice bran’s mechanism of improving dyslipidemia, promoting the browning of white fat, and regulating the anti-obesity mechanism of intestinal flora is still unclear. Therefore, this research group studied the effects of high-fat diet feeding on obesity, blood lipids and metabolic abnormalities in mice, and used rice bran for diet intervention in order to explore the effects of rice bran on blood lipid levels, inflammatory factor levels, brown fat activity, and intestinal effects in obese individuals. The regulating effect of the Tao microbiota reveals its possible potential mechanism in the anti-obesity effect, and provides a scientific theoretical basis for the development of related functional edible rice bran ingredients with weight loss effects.
Related research results were published in Food & Function with the title”Rice bran attenuated obesity via alleviating dyslipidemia, browning of white adipocytes and modulating gut microbiota in high-fat diet-induced obese mice”. Associate Professor He Rong is the corresponding author . This research was funded by a national key research and development project.
link to the original text:https://doi.org/10.1039/C9FO01524H