The agricultural industry standard”Feed in Feed”, developed by the chief researcher Su Xiaoou of the”Feed Quality and Safety Testing and Evaluation” Innovation Team of the Institute of Agricultural Quality Standards and Testing Technology, Chinese Academy of Agricultural Sciences The Determination of 37 Mycotoxins by Liquid Chromatography Tandem Mass Spectrometry (NY/T 3803-2020) was published on November 12, 2020, Ministry of Agriculture and Rural Affairs Announcement No. 357, and will be implemented on April 1, 2021.
Mycotoxin contamination in feed and agricultural products is a global problem that poses serious challenges to agricultural production and food safety. Due to many types of mycotoxins, large structural differences, and complex sample matrices, high-throughput detection of multiple toxins has always been a bottleneck. At present, most of the detection standards and methods reported in the literature are the detection of single or single type of mycotoxins. The innovation team of”Feed Quality and Safety Inspection and Evaluation” focused on the practical problems of simultaneous contamination of multiple mycotoxins in feed. It started from basic theories and took 5 years to tackle key problems. Based on a large amount of experimental data, it proposed the principle of multi-mechanism impurity adsorption and developed The impurity adsorption purification column is suitable for simultaneous purification of 5 types of 37 mycotoxins in the feed matrix, which solves the serious interference of the sample matrix, and takes into account the huge differences in the structure and physical and chemical properties of different types of hazards. The sample purification time is from More than 40 minutes can be shortened to less than 2 minutes; the agricultural industry standard”Determination of 37 Mycotoxins in Feed by Liquid Chromatography Tandem Mass Spectrometry” is developed based on the multi-mechanism impurity adsorption purification column. The standard method with the largest number of simultaneous determinations of”one purification, one machine”; applying this method to participate in the 2016 European Union, 2018 and 2019 Asia-Pacific region feed raw material mycotoxin simultaneous testing international laboratory proficiency test, the results are all satisfactory. The successful development of this standard detection method has expanded the scope of monitoring mycotoxins in my country’s feed and livestock products and improved the ability to detect risks.
The research authorized 1 national invention patent and published 3 research papers in domestic and foreign journals; the formed multi-mechanism impurity adsorption purification technology has been applied to Beijing Hexagon The transfer of Biotechnology Co., Ltd. realized the deep integration of”production, learning, and research”.
Figure 1. Multi-mechanism impurity adsorption technology greatly improves detection Performance