Notice of the Ministry of Agriculture and Rural Affairs on Issuing the National Animal Disease Compulsory Immunization Program in 2021
By: Date: 2021-01-12 Categories: authoritativerelease Tags: ,
Departments (bureaus, commissions) of agriculture and rural areas (agriculture and animal husbandry, animal husbandry and veterinary medicine) of all provinces, autonomous regions, municipalities directly under the Central Government and cities under separate state planning, Xinjiang Production and Construction Corps Agriculture and Rural Affairs Bureau, and related institutions:

   In order to effectively do a good job in compulsory immunization against animal diseases nationwide in 2021, in accordance with the provisions of the Animal Epidemic Prevention Law of the People’s Republic of China and the current animal epidemic prevention practices, our Ministry organized the formulation The”National Animal Disease Compulsory Immunization Program in 2021″ was completed. You are hereby issued, please follow and implement.

   Ministry of Agriculture and Rural Affairs

   January 6, 2021

  2021 National Animal Disease Compulsory Immunization Program

   1. Immune disease types and requirements

   (1) Immune diseases

   highly pathogenic avian influenza, foot-and-mouth disease, petitella ruminant, brucellosis, hydatid disease.

   (2) Immunization requirements

   Highly pathogenic avian influenza, foot-and-mouth disease, Peste des petits ruminants, brucellosis, and hydatid disease should maintain a population immune density of more than 90%throughout the year. Among them, the immune density of livestock and poultry should reach 100%. The qualified rate of immune antibodies for highly pathogenic avian influenza, foot-and-mouth disease, and petit ruminant disease should be maintained at more than 70%all year round.

   (3) Types and areas of immune animals

   Highly pathogenic avian influenza:For all chickens, ducks, geese, quail and other artificially raised poultry in the country, the H5 and H7 subtypes are highly pathogenic Immunization to sexual avian influenza. For poultry used for research and vaccine production, importing countries (regions) expressly require that no highly pathogenic avian influenza immunization is required for export poultry, and those that are not immunized due to other special reasons, the relevant farm households shall be reported to the provincial animal husbandry and veterinary supervisor level by level After the department agrees, immunization may not be implemented.

   Foot-and-mouth disease:All cattle, sheep, camels, and deer nationwide will be immunized against Type O and Type A foot-and-mouth disease (provinces and provinces that have formulated compulsory immunization plans or completed vaccine bidding Cities with separate plans may still be implemented in accordance with the relevant requirements of the National Animal Disease Compulsory Immunization Program in 2020). All pigs across the country will be immunized against type O foot-and-mouth disease, and localities will determine whether to implement type A foot-and-mouth disease immunization for pigs based on the results of the assessment. This will be implemented with the consent of the provincial animal husbandry and veterinary department.

   Petit Ruminant Epidemic:Immunize all sheep in the country against Petit Ruminant Epidemic. To carry out the construction of non-immune areas without immunization against animal diseases of ruminants and areas that have withdrawn from compulsory immunization, the provincial animal husbandry and veterinary authorities may not implement immunization after approval.

   Brucellosis:In areas such as brucellosis, breeding animals are prohibited from being immunized, and cattle and sheep other than breeding animals are immunized against brucellosis Each province shall determine whether to immunize dairy animals on its own based on the evaluation results. If immunization is really necessary, the relevant farm households can report to the provincial animal husbandry and veterinary authority for approval, and then take immunization measures on a farm basis; each province shall, based on the evaluation situation, Determining non-immune purification areas shall be implemented after approval by the provincial animal husbandry and veterinary authority. In Brucellosis Type II areas, immunization of cattle and sheep is prohibited in principle. If immunization is really needed, farmers can report to the provincial animal husbandry and veterinary department for approval, and then immunize them on a farm basis.

   echinococcosis:In echinococcosis endemic areas, program immunization of breeding sheep, and timely immunization of newborn lambs and lambs; Sichuan, Tibet, In Gansu, Qinghai and other provinces with high incidence of echinococcosis, with the approval of the provincial animal husbandry and veterinary department, 5 times the dose of the genetic engineering subunit vaccine of sheep hydatid disease can be used to pilot compulsory yak immunization; China’s animal disease prevention and control The center should guide the provincial animal disease prevention and control center to carry out the monitoring and evaluation of the immunization effect, and provide technical support for the comprehensive implementation of the compulsory immunization of cattle echinococcosis in the next step.

   Swine fever and highly pathogenic blue ear disease of swine, immunization shall be carried out in accordance with the prevention and control requirements of the national prevention and control guidelines. The provincial-level animal husbandry and veterinary department may increase the types of diseases and areas for compulsory immunization based on the prevalence of animal diseases in their jurisdictions.

   2. Types of vaccines

  The highly pathogenic avian influenza, foot-and-mouth disease, petit ruminant, brucellosis, hydatid disease vaccines and catalogs approved by the country are in the attachment. For vaccine manufacturers and specific product information, please refer to the National Basic Veterinary Drug Database (

  3. Immune subjects

   Units and individuals that raise animals (breeding farm households) are the subjects of compulsory immunization, and they bear the responsibility of the subjects of compulsory immunization in accordance with the Animal Epidemic Prevention Law of the People’s Republic of China, and implement the compulsory Obligation of immunization, independent implementation of immunization, establishment of immunization files, making immunization records, and accepting supervision and inspection.

   Fourth, the division of responsibilities

   According to relevant documents of the State Council, local people’s governments at all levels are responsible for animal epidemic prevention within their jurisdictions, and organize relevant departments to implement the compulsory immunization plan according to the division of responsibilities.

   The animal husbandry and veterinary authorities at all levels specifically organize the implementation of the compulsory immunization plan, and are responsible for organizing the allocation, preservation, and use of the mandatory immunization vaccine. Animal disease prevention and control agencies at all levels and relevant national veterinary reference laboratories are responsible for carrying out the evaluation of the effect of compulsory immunization during use. Institutions at all levels responsible for animal health supervision are responsible for supervising and inspecting the performance of compulsory immunization obligations by farm households.

  The provincial animal husbandry and veterinary department, in conjunction with the provincial financial department, organizes the management of the”first payment before replenishment” fund distribution and the procurement of compulsory immunization vaccines. Animal husbandry and veterinary departments at all levels should coordinate with the financial departments at the same level to ensure that the compulsory immunization subsidy funds are in place. Other relevant departments cooperate with the implementation of the compulsory immunization plan in accordance with the law.

  5. Organization and implementation

   (1) Develop an implementation plan. All localities should formulate the implementation plan of the province’s compulsory immunization plan in a timely manner in accordance with the requirements of this plan and combining the actual prevention and control. For free-range animals, a combination of centralized immunization in spring and autumn and regular replenishment is adopted, and programmed immunization is implemented in large-scale farms and places where conditions permit.

   (2) Promote”make up before hitting”. All provinces should follow the”Notice of the General Office of the Ministry of Agriculture and Rural Affairs on Deepening the Reform of the Implementation Mechanism of the Animal Disease Compulsory Immunization Subsidy” (Nongbanmu [2020] No. 53), and formulate implementation plans based on actual conditions to accelerate the promotion of”Work, report progress on time.

   (3) Regulate vaccine procurement. Provincial-level animal husbandry and veterinary departments should work with provincial-level financial departments to strengthen the supervision and management of vaccine procurement. All regions should establish and improve their own department’s vaccine procurement system, improve the internal control system, and strictly regulate vaccine procurement activities. Vaccine procurement should be evaluated based on comprehensive indicators such as quality, immunization effect, price and after-sales service. Vaccine companies are prohibited from bidding maliciously, colluding bids, participating in bidding at a price below the cost, and propagating beyond the scope of use. Once discovered, the relevant violating companies will be blacklisted.

   (4) Carry out technical training. Before the launch of centralized immunization work in the spring, the China Animal Disease Prevention and Control Center should organize training for provincial-level immunization technicians. Animal husbandry and veterinary institutions at all levels shall organize training on immunization techniques for epidemic prevention personnel at township and village levels. Vaccine and diagnostic reagent supply companies should do a good job in training and technical services.

   (5) Improve immunization records. Township animal husbandry and veterinary institutions, village-level epidemic prevention personnel, and farm households must make immunization records to ensure that the immunization records match the livestock and poultry identification. Farm households should keep detailed records of livestock and poultry inventory, slaughter, immunization, etc., especially information about vaccine types, manufacturers, and production batch numbers.

   (6) Implement the reporting system. Provincial animal husbandry and veterinary institutions report on vaccine purchases on a monthly basis, and animal husbandry and veterinary institutions at all levels report on immunization on a monthly basis. During the spring and autumn intensive immunization period, a weekly report system is implemented on the progress of immunization. In the event of a major animal epidemic, a daily reporting system shall be implemented for emergency immunization situations. All localities must clarify that a designated person is responsible for collecting and counting immunization information, and report it to the China Animal Disease Prevention and Control Center on time, and report any problems found during the immunization process at any time.

   (7) Assess the immune effect. Animal husbandry and veterinary institutions at all levels should strengthen the monitoring and evaluation of immunization effects, and implement a combination of routine monitoring and random sampling, and organize timely supplementary exemptions if the antibody qualification rate of livestock and poultry groups does not meet the specified requirements; Farm households with supplements should organize spot checks on the immune effect to ensure the immune effect; the occurrence of side immune reactions, substandard immune antibody levels and immune failures in the jurisdiction should be investigated and handled in a timely manner. The Ministry of Agriculture and Rural Affairs will organize regular inspections and, as appropriate, organize random inspections and report the inspection results.

  VI. Supervision and management

   Breeding units and individuals who refuse to perform compulsory immunization obligations and cause animal epidemics due to inadequate immunization shall be dealt with in accordance with the law and the relevant units and personnel shall be held accountable.

   The animal husbandry and veterinary departments at all levels should strengthen the supervision and inspection of the manufacturers of mandatory immunization vaccines within their jurisdictions, and urge the manufacturers to strictly implement the Good Manufacturing Practice for Veterinary Drugs (GMP). Fully implement the”two-dimensional code” management system for veterinary drugs, strengthen vaccine tracking and full-process quality supervision, and severely crack down on the production and sale of fake and inferior vaccines.

  The China Veterinary Drug Supervision Institute shall strengthen the supervision of vaccine quality, carry out supervision and random inspection, and implement supervision and inspection of production enterprises.

  VII. Funding support

   According to the”Notice of the Ministry of Finance of the Ministry of Agriculture and Rural Affairs on Revising and Issuing the Administrative Measures for Agricultural Transfer Payment Funds” (Cainong [2020] No. 10), the country determines According to the livestock and poultry breeding volume, individual livestock and poultry subsidy standards, regional subsidy coefficients and other factors announced by the National Bureau of Statistics, the central government calculates the size of the central government’s compulsory immunization subsidy, and distributes it to the provincial finances for development. Compulsory immunization, immunization effect monitoring and evaluation, disease monitoring and purification, personnel protection, implementation of compulsory immunization plan, purchase of epidemic prevention services, etc.

   According to the actual bidding price of vaccines, the quantity required, and the actual needs of animal epidemic prevention work, each province, combined with the central financial subsidy funds, arranges provincial financial subsidy funds according to the facts, focusing on guarantees In pastoral semi-pastoral areas and remote mountainous areas, small and medium-sized farm households that have not implemented the “spot first and then make up” need for compulsory immunization to ensure the construction of an effective immune barrier.

  Attachment:Catalogue of relevant vaccines approved by the state


  Country-approved vaccine catalogue

  一. Highly pathogenic avian influenza

  recombinant avian influenza virus (H5+H7) trivalent inactivated vaccine.

  二. Foot-and-mouth disease

  1. Foot-and-mouth disease type O inactivated vaccine;

  2. Foot-and-mouth disease O-type synthetic peptide vaccine;

  3. Foot-and-mouth disease type A inactivated vaccine;

  4. Foot-and-mouth disease O-type A bivalent inactivated vaccine;

  5. Foot-and-mouth disease O-type A bivalent synthetic peptide vaccine.

  3. Peste des petits ruminants

  1. Small ruminant animal disease live vaccine;

  2. The combined live vaccine of Peste des petits ruminants and goat pox.

  4. Brucellosis

   live brucellosis vaccine.

  5. Hydatid disease

   Sheep hydatid disease genetic engineering subunit vaccine.