A few days ago,”An oral vaccine for grass carp hemorrhagic disease yeast and its application” applied by Zhou Yong and others from the Yangtze River Fisheries Research Institute of the Chinese Academy of Fishery Sciences was authorized by the national invention patent. The patent number is:ZL201910727994.X.
This invention discloses an oral vaccine for grass carp hemorrhagic disease yeast and its application. The oral vaccine involved is Saccharomyces cerevisiae expressing the fusion protein LTB-VP4. The protein has good immunogenicity and stability in the body of grass carp. The vaccine has high protection. The survival rate of grass carp after challenge is as high as 73.3%. After being made into an oral vaccine, the operation is simple and suitable for large-scale promotion.